How does CBD work? The human physique is equipped with an endocannabinoid system (ECS), which helps to maintain systems running easily. The ECS is made up of endocannabinoids, enzymes, and receptors. Your physique naturally produces endocannabinoids. The two that consultants know of are anandamide (AEA) and 2-arachidonoylglyerol (2-AG). These bind to CB1 and CB2 receptors in your physique and trigger specific effects like pain relief. Once endocannabinoids have completed their job, enzymes break them down. Since CBD is a cannabinoid, it will possibly bind to your body’s endocannabinoid receptors. But specialists don’t know how the ECS and CBD work together. Some believe that CBD stops enzymes from breaking down endocannabinoids, but that’s just one concept. What researchers are fairly sure of is that CBD and THC work higher together than alone. This occurs as a result of entourage effect. That’s why full-spectrum CBD could have more pronounced effects than different forms of CBD.

CBD is thought to work by reducing inflammation in the brain and nervous system via an effect on cannabinoid and other receptors, ion channels, anandamide (a substance that regulates our response to ache) and enzymes. A Cochrane review discovered all cannabis-primarily based medicines to be superior to placebo or conventional medication for neuropathic pain